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Fig. 7 | BMC Cancer

Fig. 7

From: Lnc-SELPLG-2:1 enhanced osteosarcoma oncogenesis via hsa-miR-10a-5p and the BTRC cascade

Fig. 7

Validation of the functions of hsa-miR-10a-5p. A Verify the performance of hsa-miR-10a-5p mimics and inhibitors using RT-qPCR. B MTS was used to determine cell viability after SaOS2 cells were transfected with mimics or inhibitors of hsa-miR-10a-5p. C Flow cytometry of apoptosis assay was used to test cell apoptosis assay after SaOS2 cells were transfected with mimics or inhibitors of hsa-miR-10a-5p. D A transwell assay was used to examine cell migration after SaOS2 cells were transfected with hsa-miR-10a-5p mimics or inhibitors. E A transwell assay was used to assess cell invasion after SaOS2 cells were transfected with hsa-miR-10a-5p mimics or inhibitors. F hsa-miR-10a-5p negatively regulated the BTRC protein expression level. (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001)

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