Table 7 Association of TP53 variation type with lymph node stage and TNM stage
From: Clinical significance of p53 protein expression and TP53 variation status in colorectal cancer
Characteristics | Total | TP53 mutation status | p | Total | TP53 mutation status | p | ||
|---|---|---|---|---|---|---|---|---|
Wild type | Missense | Wild type | Nonsense/frameshift | |||||
N stage | ||||||||
 N0 | 90 | 36 (40%) | 54 (60%) |  | 53 | 36 (67.9%) | 17 (32.1%) |  |
 N1–3 | 73 | 19 (26%) | 54 (74%) | 0.061 | 43 | 19 (44.2%) | 24 (55.8%) | 0.019 |
TNM stage | ||||||||
 Stage I, II | 92 | 37 (40.2%) | 55 (59.8%) |  | 55 | 37 (67.3%) | 18 (32.7%) |  |
 Stage III, IV | 71 | 18 (25.4%) | 53 (74.6%) | 0.047 | 41 | 18 (43.9%) | 23 (56.1%) | 0.022 |