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Table 2 TRPM7methylation in breast cancer: univariate and multivariate models with clinicopathological characteristics

From: Promoter methylation of transient receptor potential melastatin-related 7 (TRPM7) predicts a better prognosis in patients with Luminal A breast cancers

Characteristics

Univariate

Multivariate

ORa (95% CI)

P

ORa (95% CI)

P

Ageb

1.04 (0.84–1.28)

0.75

/

/

WHO gradec

0.66 (0.37–1.18)

0.16

/

/

Molecular subtyped

1.27 (1.00–1.63)

0.05

1.34 (0.94–1.90)

0.10

LNMe

0.09 (0.04–0.22)

0.001

0.09 (0.03–0.27)

0.001

ER

1.43 (0.81–2.50)

0.21

  

PR

1.33 (0.77–2.29)

0.30

  

Her2

0.61 (0.31–1.20)

0.15

  

Endocrine therapy

1.43 (0.81–2.50)

0.21

1.45 (0.76–2.76)

0.26

Radiotherapy

0.37 (0.21–0.64)

0.001

0.94 (0.36–2.44)

0.90

Chemotherapy

0.56 (0.26–1.20)

0.14

0.09 (0.31–1.97)

0.61

Relapse

0.63 (0.29–1.38)

0.25

3.25 (0.49–21.58)

0.22

Survival statusf

0.49 (0.23–1.05)

0.06

0.20 (0.03–1.21)

0.07

  1. aOR: odds ratio with 95% confidence interval; bAge (per 10 years); cWHO grade (I, II, III and IV); dMolecular subtype (Luminal A, Luminal B, Her2 positive and Basal like); eLymph node metastasis; fSurvival status (alive vs. dead)