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Table 1 Comparison of clinical factors between ALNM* and NALNM in EBC lesions

From: Prediction model of axillary lymph node status using automated breast ultrasound (ABUS) and ki-67 status in early-stage breast cancer

Variables

Total

(n = 469)

NALNM (%)

(n = 291)

ALNM (%)

(n = 178)

P

Age

   

0.651

  < 40

34

24(70.6)

10(29.4)

 

  40 ~ 49

156

100(64.1)

56(35.9)

 

  50 ~ 59

152

94(61.8)

58(38.2)

 

  60 ~ 69

99

57(57.6)

42(42.4)

 

   ≥ 70

28

16(57.1)

12(42.9)

 

Marital status

   

0.869

  Unmarried

3

2(66.7)

1(33.3)

 

  Married

466

289(62.0)

177(38.0)

 

Fertility status

   

0.893

  No

10

6(60.0)

4(40.0)

 

  Yes

459

285(62.1)

174(37.9)

 

Menopause

   

0.247

  No

240

155(64.6)

85(35.4)

 

  Yes

229

136(59.4)

93(40.6)

 

BMI

23.717 ± 3.107

23.507 ± 2.905

24.060 ± 3.384

0.061

Smoke

   

0.788

  No

462

287(62.1)

175(37.9)

 

  Yes

7

4(57.1)

3(42.9)

 

Histologic type

   

0.239

  IDC

443

273(61.6)

170(38.4)

 

  Lobular

17

10(58.8)

7(41.2)

 

  Other

9

8(88.9)

1(11.1)

 

Ki-67

   

 < 0.0001

  Negative

170

146(85.9)

24(14.1)

 

  Positive

299

145(48.5)

154(51.5)

 

P53

   

0.657

  Negative

148

94(63.5)

54(36.5)

 

  Positive

321

97(61.4)

124(38.6)

 

ER

   

0.051

  Negative

87

46(52.9)

41(47.1)

 

  Positive

382

245(64.1)

137(35.9)

 

PR

   

0.146

  Negative

122

69(56.6)

53(43.3)

 

  Positive

347

222(64.0)

125(36.0)

 

HER-2

   

0.001

  Negative

357

237(66.4)

120(33.6)

 

  Positive

112

54(48.2)

58(51.8)

 

MS

   

 < 0.0001

  Lumina A

136

119 (87.5)

17(12.5)

 

  Lumina B

254

128(50.39)

126(49.61)

 

Her-2 overexpression

42

24(57.1)

18(42.9)

 

TN

37

20(54.1)

17(45.9)

 

Location

   

0.056

  Inner lower quadrant

25

19(76.0)

6(24.0)

 

  Upper outer quadrant

294

169(57.5)

125(42.5)

 

  Outer lower quadrant

77

52(67.5)

25(32.5)

 

  Upper inner quadrant

73

51(69.9)

22(30.1)

 
  1. * ALNM Axillary lymph node metastasis, NALNM No axillary lymph node metastasis, EBC Early-stage breast cancer, BMI Body mass index, IDC Invasive ductal carcinoma, ER Estrogen-receptor, PR Progesterone-receptor, HER-2 Human epidermal growth factor receptor 2, MS Molecular subtype, TN Triple negative