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Fig. 5 | BMC Cancer

Fig. 5

From: Flagellin synergistically enhances anti-tumor effect of EGFRvIII peptide in a glioblastoma-bearing mouse brain tumor model

Fig. 5

Induction of apoptosis in brain tumor tissues. a Mice were sacrificed on day 20 for paraffin-embedded tissue. Magnification: × 200. Distribution of CD8 + lymphocytes and expression of cleaved caspase-3 in extracted mouse brain tumors after IHC staining. Each immunostaining pattern was confirmed by triplicate specimens from the same mouse and typical image was shown in Fig. 5a. b DNA destruction in brain tumor tissues after TUNEL assay. c Spots were randomly selected from three regions in tumor tissues and counted to obtain an average fluorescence signal. Significant differences are indicated by asterisk (*: p < 0.05., **: p < 0.01., ****: p < 0.0001)

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BMC Cancer

ISSN: 1471-2407

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