Model | Group by | All grade | ||||
---|---|---|---|---|---|---|
Event rate (%) | Lower limit (%) | Upper limit (%) | Z-Value | p-Value | ||
Fixed | Abdominal pain | 13.6 | 10.7 | 17.3 | −12.907 | 0.000 |
Fixed | Alanine aminotransferase increased | 17.9 | 14.8 | 21.4 | −13.234 | 0.000 |
Fixed | Cholangitis | 5.5 | 1.8 | 15.9 | −4.765 | 0.000 |
Fixed | Cough | 16.5 | 13.5 | 20.1 | −13.286 | 0.000 |
Fixed | Dizziness | 13.3 | 8.2 | 20.9 | −6.768 | 0.000 |
Fixed | Dysgeusia | 15.1 | 11.0 | 20.5 | −9.120 | 0.000 |
Fixed | Dyspnea | 14.8 | 7.6 | 26.9 | −4.566 | 0.000 |
Fixed | Electrocardiogram QT prolonged | 6.7 | 3.9 | 11.5 | −8.749 | 0.000 |
Fixed | Epistaxis | 11.6 | 7.6 | 17.3 | −8.546 | 0.000 |
Fixed | Hypoalbuminaemia | 12.3 | 8.5 | 17.4 | −9.382 | 0.000 |
Fixed | Hypokalaemia | 15.3 | 11.9 | 19.4 | −11.667 | 0.000 |
Fixed | Hyponatraemia | 8.2 | 4.8 | 13.6 | −8.334 | 0.000 |
Fixed | Increased alanine aminotransferase | 9.0 | 4.3 | 17.6 | −5.848 | 0.000 |
Fixed | Increased blood alkaline phosphatase | 11.3 | 5.8 | 21.1 | −5.473 | 0.000 |
Fixed | Increased blood bilirubin | 4.2 | 2.4 | 7.4 | −10.347 | 0.000 |
Fixed | Infusion-related reactions | 1.7 | 0.6 | 4.7 | −7.536 | 0.000 |
Fixed | Intestinal perforation | 3.8 | 0.2 | 40.3 | −2.232 | 0.026 |
Fixed | Malaise | 24.3 | 20.6 | 28.5 | −10.369 | 0.000 |
Fixed | Nasopharyngitis | 10.3 | 6.6 | 15.8 | −8.675 | 0.000 |
Fixed | Nausea | 72.3 | 69.8 | 74.6 | 15.856 | 0.000 |
Fixed | Neutropenia | 6.4 | 2.7 | 14.5 | −5.800 | 0.000 |
Fixed | Oedema | 12.2 | 8.8 | 16.7 | −10.609 | 0.000 |
Fixed | Pneumonitis | 8.2 | 5.6 | 11.9 | −11.503 | 0.000 |
Fixed | Pyrexia | 20.4 | 17.0 | 24.3 | −11.903 | 0.000 |
Fixed | Rush | 13.0 | 8.0 | 20.5 | −6.852 | 0.000 |
Fixed | Stomatitis | 22.9 | 17.9 | 28.7 | −7.797 | 0.000 |
Fixed | Upper respiratory tract infection | 11.1 | 6.7 | 17.9 | −7.319 | 0.000 |
Fixed | Weight decreased | 14.3 | 10.3 | 19.5 | −9.352 | 0.000 |
Random | Abdominal distension | 19.0 | 6.4 | 44.7 | −2.296 | 0.022 |
Random | Alopecia | 35.6 | 29.8 | 41.8 | −4.422 | 0.000 |
Random | Anaemia | 37.2 | 32.2 | 42.5 | −4.648 | 0.000 |
Random | Constipation | 26.9 | 22.4 | 31.8 | −8.174 | 0.000 |
Random | Decreased appetite | 44.3 | 35.0 | 54.1 | −1.135 | 0.256 |
Random | Decreased lymphocyte count | 12.6 | 7.3 | 20.8 | −6.325 | 0.000 |
Random | Decreased neutrophil count | 36.4 | 30.6 | 42.7 | −4.131 | 0.000 |
Random | Decreased platelet count | 29.0 | 25.0 | 33.4 | −8.565 | 0.000 |
Random | Decreased white blood cell count | 26.1 | 22.4 | 30.0 | −10.345 | 0.000 |
Random | Diarrhoea | 29.5 | 25.5 | 33.9 | −8.382 | 0.000 |
Random | Ejection fraction decreased | 3.0 | 0.6 | 14.1 | −4.075 | 0.000 |
Random | Fatigue | 38.5 | 32.4 | 45.0 | −3.426 | 0.001 |
Random | Headache | 14.6 | 8.4 | 24.2 | −5.535 | 0.000 |
Random | Increased aspartate aminotransferase | 19.5 | 14.8 | 25.2 | −8.386 | 0.000 |
Random | Interstitial lung disease | 7.5 | 4.5 | 12.1 | −9.151 | 0.000 |
Random | Vomiting | 39.2 | 33.8 | 44.9 | −3.698 | 0.000 |