Table 5 Relationship between clinicopathological factors and autoantibodies against SPP1 in ESCC patients

Mean age ± SD

63.5 ± 8.2

Age range

42–88

  <  = 60

55

0.3320 ± 0.1079

0.051

  > 60

107

0.3712 ± 0.1412

Sex

 Male

109

0.3491 ± 0.1242

0.223

 Female

53

0.3760 ± 0.1461

Smoking

 Yes

54

0.3402 ± 0.1362

0.165

 None

99

0.3718 ± 0.1330

Drinking

 Yes

45

0.3587 ± 0.1454

0.903

 None

106

0.3616 ± 0.1310

Differentiation

 Moderate and high

40

0.3728 ± 0.1520

0.344

 Low

30

0.3407 ± 0.1207

TNM stage

 I-II

49

0.3378 ± 0.1330

0.286

 III—IV

48

0.3665 ± 0.1303

Lymphatic metastasis

 Positive

53

0.3404 ± 0.1142

0.600

 Negative

52

0.3537 ± 0.1430

Distance metastasis

 Positive

14

0.3814 ± 0.1309

0.346

 Negative

85

0.3458 ± 0.1305

Family tumor history

 Yes

13

0.4623 ± 0.1587

0.004

 None

138

0.3497 ± 0.1283