Parameters | Univariable analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age ≥ 60 years | 1.028 | 0.749—1.412 | 0.863 | |||
Female | 0.872 | 0.637—1.194 | 0.394 | |||
BMI ≥ 24 kg/m2 | 0.981 | 0.721—1.333 | 0.901 | |||
ASA score 1–2 | 1.212 | 0.766—1.917 | 0.412 | |||
Primary site colon | 1.186 | 0.870—1.618 | 0.281 | |||
Right hemicolon | 1.162 | 0.778—1.736 | 0.464 | |||
R0 resectiona | 0.506 | 0.368—0.694 | < 0.001* | 0.635 | 0.455—0.887 | 0.008* |
Poorly differentiated | 1.087 | 0.758—1.559 | 0.649 | |||
T3-T4 | 1.182 | 0.656—2.128 | 0.578 | |||
N1-N2a | 1.798 | 1.231—2.626 | 0.002* | 1.512 | 1.027—2.225 | 0.036* |
Synchronous metastasis | 1.388 | 0.929—2.075 | 0.109 | |||
Extrahepatic metastasesa | 1.804 | 1.176—2.768 | 0.007* | 1.705 | 1.100—2.641 | 0.017* |
Diameter of metastases > 5 cm | 0.925 | 0.560—1.529 | 0.762 | |||
Multiple metastasesa | 1.814 | 1.316—2.501 | < 0.001* | 0.221 | ||
Bilobar distributiona | 1.899 | 1.386—2.602 | < 0.001* | 0.663 | ||
Preoperative CEA > 50 ng/mla | 1.703 | 1.190—2.437 | 0.004* | 1.500 | 1.039—2.166 | 0.030* |
Major liver resectiona | 2.159 | 1.582—2.948 | < 0.001* | 1.353 | 0.962—1.903 | 0.082** |
Hepatectomy only | 0.969 | 0.701—1.339 | 0.848 | |||
Radio frequency ablationa | 1.523 | 0.986—2.354 | 0.058 | 0.764 | ||
Preoperative chemotherapya | 1.630 | 1.177—2.258 | 0.003* | 0.856 | ||
Postoperative chemotherapya | 0.605 | 0.444—0.825 | 0.001* | 0.591 | 0.432—0.809 | 0.001* |
Comorbidity | 0.907 | 0.664—1.240 | 0.542 | |||
Postoperative complicationa | 1.832 | 1.343—2.498 | < 0.001* | 1.552 | 1.125—2.142 | 0.007* |
Postoperative major complication | 1.218 | 0.810—1.833 | 0.344 | |||
Serious operation injury conditiona | 2.072 | 1.520—2.824 | < 0.001* | 1.539 | 1.101—2.151 | 0.012* |
AMLRI > 3.33a | 2.295 | 1.430—3.684 | 0.001* | 2.162 | 1.334—3.503 | 0.002* |
AST > 14 U/L | 1.948 | 1.082—3.508 | 0.026* | |||
MLR > 0.15 | 1.618 | 0.982—2.667 | 0.059 | |||
Blood loss (ml) | 1.969 | 1.399—2.771 | < 0.001* | |||
Operation time (min) | 1.596 | 1.170—2.177 | < 0.001* | |||
CRS 3–5 | 1.788 | 1.312—2.436 | < 0.001* |