Table 2 Univariable and multivariable analysis of parameters for progression-free survival

Age ≥ 60 years

0.993

0.783—1.260

0.957

Female

0.957

0.752—1.217

0.719

BMI ≥ 24 kg/m²

0.891

0.706—1.124

0.328

ASA score 1–2

1.051

0.724—1.526

0.794

Primary site colon

1.052

0.833—1.330

0.669

Right hemicolon

1.066

0.781—1.453

0.688

R0 resection^a

0.515

0.404—0.658

< 0.001^*

0.583

0.453—0.748

< 0.001^*

Poorly differentiated^a

1.286

0.990—1.671

0.060

0.684

T3-T4^a

1.490

0.935—2.374

0.093

0.262

N1-N2^a

1.749

1.332—2.295

< 0.001^*

1.511

1.145—1.994

0.004^*

Synchronous metastasis^a

1.451

1.087—1.937

0.012^*

0.143

Extrahepatic metastases^a

1.612

1.160—2.239

0.004^*

1.416

1.015—1.976

0.041^*

Diameter of metastases > 5 cm

1.038

0.722—1.492

0.841

Multiple metastases^a

1.997

1.571—2.539

< 0.001^*

0.063

Bilobar distribution^a

2.035

1.603—2.583

< 0.001^*

0.115

Preoperative CEA > 50 ng/ml^a

1.569

1.183—2.082

0.002^*

1.400

1.053—1.861

0.021^*

Major liver resection^a

1.978

1.563—2.503

< 0.001^*

1.615

1.266—2.060

< 0.001^*

Hepatectomy only

0.869

0.678—1.113

0.267

Radio frequency ablation^a

1.818

1.289—2.565

0.001^*

0.153

Preoperative chemotherapy^a

1.481

1.170—1.874

0.001^*

0.204

Postoperative chemotherapy

0.870

0.689—1.098

0.241

Comorbidity

0.960

0.760—1.213

0.731

Postoperative complication^a

1.393

1.103—1.757

0.005^*

0.161

Postoperative major complication

1.120

0.827—1.517

0.463

Serious operation injury condition^a

1.616

1.279—2.042

< 0.001^*

0.062

AMLRI > 3.33^a

1.530

1.114—2.101

0.009^*

1.462

1.059—2.019

0.021 ^*

AST > 14 U/L

1.697

1.133—2.542

0.010^*

MLR > 0.15

1.397

0.953—2.046

0.086

Blood loss (ml)

1.521

1.157—1.999

0.003^*

Operation time (min)

1.572

1.240—1.993

< 0.001^*

CRS 3–5

1.608

1.272—2.032

< 0.001^*