Skip to main content

Table 1 Clinicopathologic characteristics of patients

From: AST·MLR index and operation injury condition are novel prognostic predictor for the prediction of survival in patients with colorectal cancer liver metastases undergoing surgical resection

Parameters

AMLRI ≤ 3.33 (n = 72)

AMLRI > 3.33 (n = 307)

All patients (n = 379)

p value

Age (years)

57(49.25–62)

57(51–65)

57(50–64)

0.378

Age ≥ 60 years

30 (41.7%)

126 (41.0%)

156 (41.2%)

0.923

Female

29 (40.3%)

115 (37.5%)

144 (38.0%)

0.657

BMI ≥ 24 kg/m2

28 (38.9%)

166 (54.1%)

194 (51.2%)

0.020*

ASA score 1–2

5 (6.9%)

36 (11.7%)

41 (10.8%)

0.240

Primary site colon

39 (54.2%)

165 (53.7%)

204 (53.8%)

0.949

Right hemicolon

13 (18.1%)

51 (16.6%)

64 (16.9%)

0.769

R0 resection

53 (73.6%)

206 (67.1%)

259 (68.3%)

0.285

Poorly differentiated

13 (18.1%)

86 (28.0%)

99 (26.1%)

0.083

T3-T4

69 (95.8%)

278 (90.6%)

347 (91.6%)

0.147

N1-N2

47 (65.3%)

217 (70.7%)

264 (69.7%)

0.369

Synchronous metastasis

58 (80.6%)

232 (75.6%)

290 (76.5%)

0.369

Extrahepatic metastases

13 (18.1%)

33 (10.7%)

46 (12.1%)

0.088

Diameter of metastases > 5 cm

6 (8.3%)

39 (12.7%)

45 (11.9%)

0.302

Multiple metastases

30 (41.7%)

173 (56.4%)

203 (53.6%)

0.025*

Bilobar distribution

16 (22.2%)

117 (38.1%)

133 (35.1%)

0.011*

Preoperative CEA > 50 ng/ml

10 (13.9%)

62 (20.2%)

72 (19.0%)

0.220

CRS 3–5

22 (30.6%)

137 (44.6%)

159 (42.0%)

0.029*

Major liver resection

19 (26.4%)

131 (42.7%)

150 (39.6%)

0.011*

Hepatectomy only

18 (25.0%)

112 (36.5%)

130 (34.3%)

0.065

Radio frequency ablation

5 (6.9%)

37 (12.1%)

42 (11.1%)

0.214

Preoperative chemotherapy

23 (31.9%)

173 (56.4%)

196 (51.7%)

< 0.001*

Postoperative chemotherapy

39 (54.2%)

154 (50.2%)

193 (50.9%)

0.541

Comorbidity

35 (48.6%)

136 (44.3%)

171 (45.1%)

0.508

Postoperative complication

36 (50.0%)

143 (46.6%)

179 (47.2%)

0.601

Postoperative major complication

7 (9.7%)

62 (20.2%)

68 (17.9%)

0.043*

Serious operation injury condition

24 (33.3%)

138 (45.0%)

162 (42.7%)

0.073

AMLRI

2.57 (1.87–3.01)

6.57 (4.92–10.09)

5.67 (3.82–8.90)

< 0.001*

AST (U/L)

16.00(13.25–18.00)

23(18–29)

21(16–27)

< 0.001*

MLR

0.16 (0.12–0.19)

0.29 (0.23–0.39)

0.27 (0.20–0.36)

< 0.001*

Blood loss (ml)

252.5 (180.0–332.5)

200 (100–400)

200 (100–400)

0.710

Operation time (min)

252.5 (180.00–332.5)

294 (184–378)

284 (180–370)

0.107

  1. BMI body mass index, ASA American Society of Anesthesiologists T tumour staging, N lymph node staging, CEA carcinoembryonic antigen, CRS clinical risk score, AMLRI AST·MLR index, AST aspartate aminotransferase, MLR monocyte-to-lymphocyte ratio
  2. *Statistically significant