Skip to main content

Table 3 Cox regression model estimates of all-cause mortality hazard ratios (HRs) with 95% confidence intervals (CIs)

From: Hospital factors and metastatic surgery in colorectal cancer patients, a population-based cohort study

 

Univariable

First model 1

Second model2

HRa (95% CI)

HRa (95% CI)

HRa (95% CI)

Hospital mCRC case load

1st quartile

1

1

1

2nd quartile

0.93 (0.87–0.99)

1.01 (0.95–1.07)

1.04 (0.98–1.11)

3rd quartile

0.97 (0.92–1.04)

1.02 (0.96–1.09)

1.07 (1.00–1.14)

4th quartile

0.87 (0.82–0.93)

0.92 (0.86–0.98)

1.06 (0.98–1.14)

Hospital level

Non-university

1

1

1

University

0.81 (.78–0.85)

0.85 (0.81–0.89)

0.83 (0.78–0.88)

  1. Model includes 9,968 patients with synchronous colorectal cancer metastases
  2. aAdjusted for time since diagnosis
  3. 1One exposure (hospital volume/ hospital level) and adjusted for sex (male, female), age (categorized: 18–64,65–79, ≥ 80 years), Charlson comorbidity index (0,1, ≥ 2), Primary tumour location (right colon, transverse colon, left colon, colon unknown location in colon, rectum), cT (1–3, 4, X) cN, (0, 1–2, X), metastases (single, multiple), civil status (married, not married), education (primary, secondary, higher education), annual income (quartiles), year of diagnosis. Missing data handled using missing indicator method
  4. 2Model of both exposures, adjusted as above