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Fig. 2 | BMC Cancer

Fig. 2

From: Metagenomes of rectal swabs in larger, advanced stage cervical cancers have enhanced mucus degrading functionalities and distinct taxonomic structure

Fig. 2

Supervised comparison of Largest tumors (LT-group) and Smallest tumors (ST-group) of MA metagenomes. a Grouping of samples into ST- and LT-groups for supervised comparison. b,c Greater richness and diversity of molecular functions in LT-group of metagenomes. d,e Density plots of differentially abundant KOs in LT- (d) and ST- (e) groups of metagenomes. Parameters of the normal distributions were used to find amplitudes of LT- and ST-abundant molecular functions among all KOs in each tumor group. f,g Density plots of all KOs identified in LT- (f) and ST- (g) groups of metagenomes. h Carbohydrate Active enZymes (CAZymes) identified in LT- and ST- groups. i Glycoside hydrolases involved in degradation of glycans (EC 3.2.1.-) are differentially enriched in LT- versus ST- group of metagenomes. j KEGG pathways enriched among KOs differentially abundant between ST- and LT- groups of metagenomes. k Some KEGG pathways differentially abundant between the groups. Phosphotransferase and putresine utilization pathway are more abundant in LT-group, while vitamin B12 production is more abundant in ST-group

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