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Table 3 Prediction performance of RS-EGFR, RS-19 and RS-21

From: Development and validation of MRI-based radiomics signatures as new markers for preoperative assessment of EGFR mutation and subtypes from bone metastases

RS

Primary training

Internal validation

External validation

AUC (95%)

ACC

SEN

SPE

AUC (95%)

ACC

SEN

SPE

AUC (95%)

ACC

SEN

SPE

RS-EGFR

0.851 (0.774-0.921)

0.800

0.722

0.870

0.780 (0.645-0.916)

0.741

0.771

0.737

0.807 (0.595-0.938)

0.625

0.765

0.857

RS-19

0.816 (0.716-0.917)

0.739

0.964

0.561

0.789 (0.636-0.942)

0.600

0.786

0.714

0.742 (0.478-0.919)

0.623

0.833

0.636

RS-21

0.814 (0.714-0.914)

0.739

0.655

0.875

0.770 (0.609-0.931)

0.657

0.800

0.700

0.792 (0.530-0.946)

0.529

0.750

0.889

  1. AUC Area under the receiver operating characteristic curve, ACC Accuracy, SEN Sensitivity, SPE Specificity, SD standard deviation