Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas

Table 1 Summary of clinical characteristics of patients with LGG in six datasets

Characteristics	TCGA dataset	CGGA_325 dataset	CGGA_693 dataset	GSE16011 dataset	GSE61374 dataset	Rembrandt dataset
No. of patients	457	172	379	103	137	141
Platform	Illumina RNAseq	Illumina HiSeq	Illumina HiSeq	Affymetrix U133 Plus 2.0 Array	Affymetrix U133 Plus 2.0 Array	Affymetrix U133 Plus 2.0 Array
Age (years)
Range	14–87	10–74	11–69	23–81	21–80	17–87
Median	41	39	40	44	41	42
Gender
Female	201	66	167	36	53	47
Male	256	106	212	67	84	72
Unknown	0	0	0	0	0	22
WHO grade
II	216	98	153	22	61	76
III	241	74	226	81	76	65
IDH mutation status
Yes	369	125	262	45	115
No	86	44	80	37	22
Unknown	2	1	37	21	0
1p/19q codeletion status
Yes	151	55	122	37	37
No	306	115	255	39	100
Unknown	0	2	2	27	0
Oveall survival (year)
Range	0.01–17.34	0.06–13.18	0.14–13.78	0.19–20.68	0–17.7	0.08–20.69
Median	1.22	6.05	3.98	3.3	4.4	3.16

ISSN: 1471-2407