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Table 1 Summary of clinical characteristics of patients with LGG in six datasets

From: Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas

Characteristics TCGA
dataset
CGGA_325
dataset
CGGA_693
dataset
GSE16011
dataset
GSE61374
dataset
Rembrandt
dataset
No. of patients 457 172 379 103 137 141
Platform Illumina RNAseq Illumina HiSeq Illumina HiSeq Affymetrix U133 Plus 2.0 Array Affymetrix U133
Plus 2.0 Array
Affymetrix U133
Plus 2.0 Array
Age (years)
 Range 14–87 10–74 11–69 23–81 21–80 17–87
 Median 41 39 40 44 41 42
Gender
 Female 201 66 167 36 53 47
 Male 256 106 212 67 84 72
 Unknown 0 0 0 0 0 22
WHO grade
 II 216 98 153 22 61 76
 III 241 74 226 81 76 65
IDH mutation status
 Yes 369 125 262 45 115  
 No 86 44 80 37 22  
 Unknown 2 1 37 21 0  
1p/19q codeletion status
 Yes 151 55 122 37 37  
 No 306 115 255 39 100  
 Unknown 0 2 2 27 0  
Oveall survival (year)
 Range 0.01–17.34 0.06–13.18 0.14–13.78 0.19–20.68 0–17.7 0.08–20.69
 Median 1.22 6.05 3.98 3.3 4.4 3.16