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Fig. 5 | BMC Cancer

Fig. 5

From: Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas

Fig. 5

Identification of IEV signature genes across LGG patients. A The venn diagram represented the number of DEGs between each two clusters and 607 DEGs were identified as IEV signature genes. B The heatmap represented the levels of IEV signature genes. C Gene ontology biological processes analysis were performed to recognized the enriched terms of IEV signature genes. D Kaplan–Meier survival curves showed the distinct prognosis of Cluster S1 (n = 219), Cluster S2 (n = 100) and Cluster S3 (n = 138). E The forest plot showed the results of univariate Cox regression analysis and indicated that the Cluster S2 is a risk factor compared with other two Clusters. F The boxplots showed the distinct levels of 19 well-designed biological processes enrichment among the three IEG-Clusters.The labelled asterisk indicated the statistical p value (ns p > 0.05 and ***p < 0.001)

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