Fig. 4

The distinct IE clusters showed different immune infiltrations levels. A The bar plots represented the proportions of different IDH mutation and 1p/19q co-deletion status among the three IE clusters. B-C The violin plots showed the distinct levels of ESTIMATE score and tumor purity among the three IE clusters. D Three-dimensional principal component analysis (PCA) indicated that the three IE clusters had distinct whole transcriptional expression profiles. E The heatmap showed the 28 types of immune cell infiltration levels among the three IE clusters by using ssGSEA algorithm. F The boxplots showed the 17 immune cell discrepancies among the three IE clusters by performing CIBERSORT deconvolution algorithm. The labelled asterisk indicated the statistical p value (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)