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Fig. 7 | BMC Cancer

Fig. 7

From: Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer

Fig. 7

Validation of KRT7 high expression in PC and its association with poor prognosis in TCGA and PUMCH cohorts. A Representative images of IHC staining of KRT7 in normal and PC tissues from HPA database. B Comparison of KRT7 expression between normal samples (GTEx dataset) and tumor samples (TCGA dataset). TCGA patients were stratified into the low-risk and high-risk groups based on the risk score of individuals. C The Kaplan–Meier survival analysis based on KRT7 expression in TCGA cohort. D The comparison of KRT7 expression between gender, grade and survival status subgroups in TCGA cohort. E Representative images of IHC staining of KRT7 in PUMCH cohort (n = 55). F The comparison of KRT7 IHC scores between AJCC stage, N stage and survival status subgroups, and proportions of these characteristics between KRT7 low- and high-expression subgroups in PUMCH cohort. Low expression, IHC scores 1 − 6; high expression, IHC scores 8 − 12. Patients were stratified into the low- and high-expression groups based on the median IHC score (median value = 6). G The Kaplan–Meier survival analysis of 55 PDAC patients from PUMCH cohort. ns, not significant; *, P < 0.05, **, P < 0.01 and ***, P < 0.001

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BMC Cancer

ISSN: 1471-2407

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