Fig. 3

Functional annotation and analysis of immunological characteristics based on risk subgroups. A-B Using GO terms of biological processes and KEGG pathway analysis, bubble plots show 10 immune-related functional annotations of differentially expressed genes between the Risk-H and Risk-L groups. C-D Comparison of the abundance of innate and adaptive immune cell infiltration between two risk subgroups in the TCGA cohort. E The correlation between the RiskScore value and 6 immune cells was estimated by the TIMER algorithm. F The abundance of 11 immune functions by ssGSEA algorithm in the Risk-H and Risk-L groups in the TCGA cohort. *P < 0.05, **P < 0.01, and ***P < 0.001