Fig. 2

Relationship between the RiskScore value and clinical characteristics and construction of nomogram model. A The heatmap shows the expression levels of the 3 signature genes in the Risk-H and Risk-L groups. The distribution of clinical characteristics and C1/2 subgroups was compared between the Risk-H and Risk-L groups in the TCGA cohort. B The Kaplan–Meier survival curve of the prognostic signature predicts the Risk-H and Risk-L groups in the TCGA cohort. C-D The Kaplan-Meier survival curves predict the OS of the LGG patients receiving different treatment strategies in the TCGA cohorts. E The nomogram model predicts the patient’s OS. Each variable’s points on the point scale are totaled. Finally, beneath the total points, the probability of 1-, 3-, or 5-year survival is projected on the scales below. F Calibration curves of the nomogram model in terms of the agreement between predicted and observed 1-, 3- and 5-year outcomes. G ROC curves showed the predictive efficiency of the RiskScore value, nomogram model, grade, 1p/19q codeletion status, and age on the 3-year survival rate. *P < 0.05, **P < 0.01, and ***P < 0.001