Table 1 Clinical and histopathologic characteristics of IDC patients
Characteristics | Train Cohort | P value | Validation Cohort | ||
|---|---|---|---|---|---|
HER2 + (n = 42) | HER2-(n = 86) | HER2 + (n = 28) | HER2-(n = 58) | ||
Ki-67 | 47.98 ± 20.51 | 33.35 ± 23.04 | 0.94 | 46.25 ± 23.16 | 34.62 ± 27.30 |
Patient age | Â | Â | 0.166 | Â | Â |
  < 35 (youth) |  | 1(1.16) |  | 3(10.71) | 1(1.72) |
 30–50 (middle-aged) | 26(61.90) | 60(69.77) |  | 17(60.71) | 36(62.07) |
  > 50 (menopause) | 16(38.10) | 25(29.07) |  | 8(28.57) | 21(36.21) |
Location = Central District |  |  | 0.243 |  |  |
 No | 38(90.48) | 73(84.88) |  | 24(85.71) | 55(94.83) |
 Yes | 4(9.52) | 13(15.12) |  | 4(14.29) | 3(5.17) |
Position = upper-right quadrant |  |  | 0.209 |  |  |
 No | 32(76.19) | 63(73.26) |  | 18(64.29) | 39(67.24) |
 Yes | 10(23.81) | 23(26.74) |  | 10(35.71) | 19(32.76) |
Position = Lower-right quadrant |  |  | 0.5 |  |  |
 No | 34(80.95) | 75(87.21) |  | 24(85.71) | 52(89.66) |
 Yes | 8(19.05) | 11(12.79) |  | 4(14.29) | 6(10.34) |
Position = Upper left quadrant |  |  | 0.463 |  |  |
 No | 25(59.52) | 52(60.47) |  | 20(71.43) | 36(62.07) |
 Yes | 17(40.48) | 34(39.53) |  | 8(28.57) | 22(37.93) |
Position = Lower left quadrant |  |  | 0.05 |  |  |
 No | 37(88.10) | 78(90.70) |  | 22(78.57) | 47(81.03) |
 Yes | 5(11.90) | 8(9.30) |  | 6(21.43) | 11(18.97) |
Histologicalgrades | Â | Â | 0.256 | Â | Â |
 Stage I | 1(2.38) | 5(5.81) |  |  | 9(15.52) |
 Stage II | 11(26.19) | 56(65.12) |  | 12(42.86) | 32(55.17) |
 Stage III | 30(71.43) | 25(29.07) |  | 16(57.14) | 17(29.31) |
Lymph node metastasis | Â | Â | 0.534 | Â | Â |
 0 | 24(57.14) | 51(59.30) |  | 13(46.43) | 29(50.00) |
 1 | 9(21.43) | 21(24.42) |  | 7(25.00) | 19(32.76) |
 2 | 5(11.90) | 9(10.47) |  | 6(21.43) | 6(10.34) |
 3 | 4(9.52) | 5(5.81) |  | 2(7.14) | 4(6.90) |