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Fig. 6 | BMC Cancer

Fig. 6

From: Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma

Fig. 6

The inhibitory effect of SSE in vivo. 786-O cells grew as subcutaneous tumors in two groups of athymic mice (5 mice per group) for 30 days. In the last 2 weeks, the mice were treated with saline or 2 mg/kg SSE every other day. A Tumor images in the two groups. Tumor volumes (B), tumor weights (C) and mouse weights (D) were measured in the two groups. E Representative images (Scale bar = 100 μm) of the tumor stained with TUNEL. Blue spots represent cell nuclei and yellow spots represent TUNEL-positive cells. F The expression of E-cadherin, VEGF and cleaved caspase-3, p-p65 and p65 were analyzed by western blot. β-Actin was used as loading control. Data are presented as means ± SD. *P < 0.05 and **P < 0.01.

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