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Table 5 Prevalence of and factors associated with hr-HPV E6/E7 mRNA expression

From: High prevalence of and factors associated with human papillomavirus infection among women attending a tertiary hospital in Gauteng Province, South Africa

Characteristics Total Hr-HPV E6/E7 mRNA prevalence Bivariate analysis Multivariate analysis
n n (%) PR (95% CI) p-value PR (95% CI) p-value
Age (years)
 18–29 86 60 (69.8) 1.00   1.00  
 30–39 78 69 (88.5) 1.27 (1.08–1.49) 0.0038 1.27 (1.08–1.49) 0.0038
 40–49 59 57 (96.6) 1.38 (1.20–1.60)  < 0.0001 1.38 (1.20–1.60)  < 0.0001
 50–68 30 27 (90.0) 1.29 (1.07–1.55) 0.0065 1.29 (1.07–1.55) 0.0065
Marital status
 Single 196 162 (82.7) 1.00    
 Married 39 33 (84.6) 1.02 (0.89–1.16) 0.80   
 Divorced/widowed/separated 18 18 (100) Not estimable    
Employment status
 Employed 85 71 (83.5) 1.00    
 Unemployed 168 142 (84.5) 1.01 (0.90–1.13) 0.84   
Place of residence
 Semi-urban 220 183 (83.2) 1.00    
 Semi-rural/Rural 33 30 (90.9) 1.09 (0.97–1.24) 0.16   
Number of children
 None 44 33 (75.0) 1.00    
 1 or 2 148 126 (85.1) 1.14 (0.94–1.3) 0.18   
 3 or more 61 54 (88.5) 1.18 (0.97–1.43) 0.092   
Present sexual activity status
 Not active 57 47 (82.5) 1.00    
 Active 196 166 (84.7) 1.03 (0.90–1.17) 0.69   
Number of current sex partners
 None 55 47 (85.5) Ref    
 1 178 149 (83.7) 0.98 (0.86–1.11) 0.75   
 2 or more 20 17 (85.0) 0.99 (0.80–1.23) 0.96   
Number of past sexual partners over 12 months
 None 52 45 (86.5) 1.00    
 1 91 70 (76.9) 0.89 (0.76–1.04) 0.14   
 2 43 38 (88.4) 1.02 (0.88–1.19) 0.79   
 3 32 27 (84.4) 0.98 (0.81–1.17) 0.79   
 4 or more 35 33 (94.3) 1.09 (0.95–1.25) 0.21   
Use of contraceptives
 Not using 180 149 (82.8) 1.00    
 Using 73 64 (87.7) 1.06 (0.95–1.18) 0.30   
Period of contraceptive use
 6 – 24 months 45 37 (82.2) 0.99 (0.85–1.16) 0.93   
 More than 24 months 28 27 (96.4) 1.16 (1.06–1.28) 0.0022   
 N/A 180 149 (82.8) 1.00    
Pregnant
 Not pregnant 202 174 (86.1) 1.00    
 Pregnant 46 34 (73.9) 0.89 (0.77–1.04) 0.147   
 Don’t know 5