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Table 2 Comparative clinico-pathological characteristics and risk group assignments in the study cohort between clinical based characterisation (DRE + systematic sampling only) versus MRI based characterisation (MRI staging and combined MRI targeted and systematic sampling) in MRI-prebiopsy cohort. *no T4 cases in this cohort, see methods for how stage was assigned for clinical and MRI assignment. European Association of Urology (EAU), American Urological Association, Cambridge Prognostic Group (CPG)

From: Assessing the impact of MRI based diagnostics on pre-treatment disease classification and prognostic model performance in men diagnosed with new prostate cancer from an unscreened population

 

Clinical stage and systematic biopsies

MRI stage and target systematic biopsies

Comparison

n

Percentage (%)

n

Percentage (%)

(%)

Stage *

  T1-T2

263

71.1

234

63.2

-7.8

  T3

107

28.9

136

36.8

7.8

Grade Group

  1

101

27.3

96

25.9

-1.4

  2

123

33.2

133

35.9

2.7

  3

60

16.2

63

17.0

0.8

  4

13

3.5

17

4.6

1.1

  5

57

15.4

61

16.5

1.1

  Benign

16

4.3

-

-

-4.3

EAU (Cancers only)

(n = 354)

(n = 370)

 

Low risk

67

18.9

66

17.8

-1.1

Intermediate risk

155

43.8

143

38.7

-5.1

High

132

37.3

161

43.5

6.2

AUA (Cancers only)

  Low risk

67

18.9

66

17.8

-1.1

  Favourable intermediate risk

86

24.3

78

21.1

-3.2

  Unfavourable intermediate risk

69

19.5

65

17.6

-1.9

  High risk

132

37.3

161

43.5

6.2

CPG (Cancers only)

  1

67

18.9

66

17.8

-1.1

  2

86

24.3

78

21.1

-3.2

  3

69

19.5

65

17.6

-1.9

  4

64

18.1

83

22.4

4.3

  5

68

19.2

78

21.1

1.9