Table 7 Multivariate Cox regression analyses of overall survival for four molecular subtypes of T1b breast cancer patients in the matched cohort

GRADE

 I

reference

reference

reference

reference

 II

0.82(0.52–1.29)

0.39

0.74(0.30–1.85)

0.52

0.83(0.10–6.79)

0.87

1.29(0.31–5.44)

0.73

 III

0.93(0.58–1.48)

0.76

0.88(0.35–2.23)

0.79

0.87(0.11–6.77)

0.89

1.32(0.32–5.42)

0.70

SURGERY

 Breast-conserving

reference

reference

reference

reference

 Total mastectomy

1.14(0.61–2.11)

0.68

0.64(0.28–1.46)

0.29

0.28(0.09–0.84)

0.02

1.65(0.77–3.54)

0.20

 Modified radical mastectomy

1.64(0.81–3.30)

0.17

1.05(0.34–3.23)

0.94

0.40(0.09–1.70)

0.21

1.79(0.72–4.44)

0.21

RADIATION

 No

reference

reference

reference

reference

 Yes

0.63(0.35–1.14)

0.13

0.59(0.27–1.27)

0.18

0.33(0.10–1.06)

0.06

0.93(0.45–1.93)

0.84

CHEMOTHERAPY

 No

reference

reference

reference

reference

 Yes

0.94(0.66–1.34)

0.74

0.38(0.21–0.66)

 < 0.01

0.51(0.23–1.15)

0.01

0.44(0.28–0.67)

 < 0.0001

AGE (year)

 < 60

reference

reference

reference

reference

 ≥ 60

3.92(2.67–5.74)

 < 0.0001

4.93(2.37–10.28)

 < 0.0001

2.34(0.87–6.32)

0.09

3.34(1.81–6.15)

 < 0.0001