Table 6 Multivariate Cox regression analyses of overall survival for tumor grades of T1a breast cancer patients in the matched cohort
Variable | T1a: GRADEI | T1a: GRADEII | T1a: GRADEIII | |||
|---|---|---|---|---|---|---|
Multivariate Analysis | Multivariate Analysis | Multivariate Analysis | ||||
HR (95%CI) | P-value | HR (95%CI) | P-value | HR (95%CI) | P-value | |
SURGERY | ||||||
Breast-conserving | reference | reference | reference | |||
Total mastectomy | 0.36(0.03–3.94) | 0.41 | 2.13(0.59–7.72) | 0.25 | 0.52(0.14–1.90) | 0.32 |
Modified radical mastectomy | 0.54(0.03–10.37) | 0.68 | 1.99(0.46–8.65) | 0.36 | 0.29(0.05–1.78) | 0.18 |
RADIATION | ||||||
No | reference | reference | reference | |||
Yes | - | - | 1.78(0.52–6.12) | 0.36 | 0.23(0.06–0.87) | 0.03 |
CHEMOTHERAPY | ||||||
No | reference | reference | reference | |||
Yes | 2.54(0.49–13.09) | 0.27 | 1.00(0.51–1.94) | 0.99 | 1.27(0.56–2.91) | 0.57 |
SUBTYPE | ||||||
HoR + /HER2- | reference | reference | reference | |||
HoR + /HER2 + | - | - | 0.22(0.06–0.75) | 0.02 | 0.10(0.01–0.79) | 0.03 |
HoR-/HER2 + | 1.73(0.20–15.15) | 0.62 | 1.00(0.43–2.33) | 1.00 | 0.68(0.22–2.15) | 0.52 |
HoR-/HER2- | - | - | 1.13(0.44–2.93) | 0.80 | 0.58(0.21–1.57) | 0.28 |
AGE (year) | ||||||
< 60 | reference | reference | reference | |||
≥ 60 | 0.31(0.03–3.20) | 0.32 | 3.35(1.64–6.83) | < 0.01 | 2.89(1.25–6.68) | 0.01 |