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Table 5 Univariate and multivariate analyses of predictors for long-term survival with Cox proportional hazards model

From: Risk factors for rebleeding and long-term outcomes in patients with head and neck cancer bleeding: a multicenter study

 

Univariate

Multivariate

 

HR(95%CI)

P value

HR(95%CI)

P value

Age

0.99(0.97,1.003)

0.986

  

Male

0.81(0.42,1.54)

0.517

  

BMI

  Underweight

2.21(1.48,3.28)

 < 0.001

1.89(1.22,2.93)

0.004*

  Normal weight

Reference

 

Reference

 

  Overweight-to-obesity

0.47(0.26,0.85)

0.012

0.75(0.39,1.43)

0.379

Cancer site

  Oral cavity

Reference

 

Reference

 

  Nasopharynx

1.31(0.77,2.23)

0.312

0.95(0.47,1.90)

0.881

  Oropharynx

1.26(0.76,2.11)

0.373

1.14(0.63,2.07)

0.664

  Hypopharynx

2.04(1.28,3.25)

0.003

1.43(0.85,2.40)

0.179

  Larynx

0.98(0.46,2.09)

0.965

0.65(0.30,1.44)

0.291

  Smoking history

1.09(0.69,1.73)

0.712

  

  SBP < 90 (mmHg)

1.76(0.95,3.28)

0.074

  

  Heart rate > 110 (beats/min)

2.00(1.38,2.88)

 < 0.001

1.58(1.04,2.39)

0.032*

  Hypertension

0.72(0.49,1.04)

0.082

  

  Diabetes mellitus

0.77(0.50,1.19)

0.235

  

  Surgical resection

0.60(0.42,0.86)

0.005

0.86(0.53,1.39)

0.856

  Chemoradiation

3.15(1.83,5.42)

 < 0.001

2.31(1.18,4.52)

0.015*

  Neck dissection

0.88(0.62,1.26)

0.495

  

  Flap reconstruction

0.96(0.66,1.39)

0.813

  

  T stage

1.36(1.14,1.63)

0.001

1.16(0.94,1.42)

0.162

  N stage

1.25(1.06,1.47)

0.008

1.11(0.90,1.37)

0.337

  M stage

1.76(0.94,3.29)

0.075

  

  Local recurrence

1.93(1.35,2.76)

 < 0.001

1.74(1.14,2.67)

0.011*

  Second primary cancer

1.37(0.93,2.00)

0.108

  

  WBC > 11.0 (103/\(\mathrm{\mu l}\))

1.48(1.03,2.12)

0.034

1.31(0.88,1.96)

0.190

  Hb < 10.0 (g/dl)

1.90(1.35,2.73)

 < 0.001

1.15(0.75,1.76)

0.530

  PLT < 150 (103/\(\mathrm{\mu l}\))

1.22(0.76,1.96)

0.401

  
  1. HR Hazard ratio, 95% CI 95% Confidence interval
  2. *P value < 0.05