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Table 4 Univariate and multivariate analyses of predictors for rebleeding with Cox proportional hazards model

From: Risk factors for rebleeding and long-term outcomes in patients with head and neck cancer bleeding: a multicenter study

 

Univariate

Multivariate

 

HR(95%CI)

P value

HR(95%CI)

P value

Age

0.98(0.97,1.002)

0.084

  

Male

1.49(0.65,3.39)

0.343

  

BMI

  

0.95(0.90,0.99)

0.041*

  Underweight

1.13(0.71,1.80)

0.605

1.15(0.72,1.84)

0.570

  Normal weight

Reference

 

Reference

 

  Overweight-to-obesity

0.44(0.24,0.80)

0.007

0.52(0.28,0.98)

0.043*

Cancer site

  Oral cavity

Reference

 

Reference

 

  Nasopharynx

1.21(0.68,2.16)

0.516

1.31(0.70,2.45)

0.400

  Oropharynx

1.17(0.69,2.00)

0.563

1.37(0.80,2.35)

0.257

  Hypopharynx

1.27(0.76,2.12)

0.364

1.30(0.77,2.21)

0.325

  Larynx

2.20(1.15,4.22)

0.017

2.13(1.07,4.23)

0.031*

Smoking history

1.34(0.79,2.27)

0.282

  

SBP < 90 (mmHg)

0.97(0.427,2.22)

0.950

  

Heart rate > 110 (beats/min)

1.39(0.93,2.07)

0.109

  

Hypertension

0.79(0.54,1.17)

0.793

  

Diabetes mellitus

0.62(0.38,1.001)

0.050

  

Surgical resection

0.82(0.56,1.19)

0.290

  

Chemoradiation

2.04(1.24,3.35)

0.005

1.49(1.001,2.94)

0.049*

  Neck dissection

0.92(0.63,1.33)

0.646

  

  Flap reconstruction

1.04(0.71,1.53)

0.830

  

  T stage

1.15(0.97,1.37)

0.105

  

  N stage

1.10(0.93,1.30)

0.279

  

  M stage

0.88(0.41,1.89)

0.739

  

  Local recurrence

1.45(0.99,2.13)

0.054

  

Second primary cancer

1.57(1.06,2.33)

0.026

1.75(1.13,2.70)

0.012*

  WBC > 11.0 (103/\(\mathrm{\mu l}\))

1.40(0.95,2.06)

0.088

  

  Hb < 10.0 (g/dl)

0.88(0.60,1.30)

0.529

  

  PLT < 150 (103/\(\mathrm{\mu l}\))

1.08(0.63,1.83)

0.787

  
  1. HR Hazard ratio, 95% CI 95% confidence interval
  2. SBP Systolic blood pressure
  3. *P value < 0.05