Univariate | Multivariate | |||
---|---|---|---|---|
HR(95%CI) | P value | HR(95%CI) | P value | |
Age | 0.98(0.97,1.002) | 0.084 | ||
Male | 1.49(0.65,3.39) | 0.343 | ||
BMI | 0.95(0.90,0.99) | 0.041* | ||
Underweight | 1.13(0.71,1.80) | 0.605 | 1.15(0.72,1.84) | 0.570 |
Normal weight | Reference | Reference | ||
Overweight-to-obesity | 0.44(0.24,0.80) | 0.007 | 0.52(0.28,0.98) | 0.043* |
Cancer site | ||||
Oral cavity | Reference | Reference | ||
Nasopharynx | 1.21(0.68,2.16) | 0.516 | 1.31(0.70,2.45) | 0.400 |
Oropharynx | 1.17(0.69,2.00) | 0.563 | 1.37(0.80,2.35) | 0.257 |
Hypopharynx | 1.27(0.76,2.12) | 0.364 | 1.30(0.77,2.21) | 0.325 |
Larynx | 2.20(1.15,4.22) | 0.017 | 2.13(1.07,4.23) | 0.031* |
Smoking history | 1.34(0.79,2.27) | 0.282 | ||
SBP < 90 (mmHg) | 0.97(0.427,2.22) | 0.950 | ||
Heart rate > 110 (beats/min) | 1.39(0.93,2.07) | 0.109 | ||
Hypertension | 0.79(0.54,1.17) | 0.793 | ||
Diabetes mellitus | 0.62(0.38,1.001) | 0.050 | ||
Surgical resection | 0.82(0.56,1.19) | 0.290 | ||
Chemoradiation | 2.04(1.24,3.35) | 0.005 | 1.49(1.001,2.94) | 0.049* |
Neck dissection | 0.92(0.63,1.33) | 0.646 | ||
Flap reconstruction | 1.04(0.71,1.53) | 0.830 | ||
T stage | 1.15(0.97,1.37) | 0.105 | ||
N stage | 1.10(0.93,1.30) | 0.279 | ||
M stage | 0.88(0.41,1.89) | 0.739 | ||
Local recurrence | 1.45(0.99,2.13) | 0.054 | ||
Second primary cancer | 1.57(1.06,2.33) | 0.026 | 1.75(1.13,2.70) | 0.012* |
WBC > 11.0 (103/\(\mathrm{\mu l}\)) | 1.40(0.95,2.06) | 0.088 | ||
Hb < 10.0 (g/dl) | 0.88(0.60,1.30) | 0.529 | ||
PLT < 150 (103/\(\mathrm{\mu l}\)) | 1.08(0.63,1.83) | 0.787 |