Association between metabolic syndrome, C-reactive protein, and the risk of primary liver cancer: a large prospective study

Table 3 Hazard ratios (HRs) for the association of metabolic syndrome and hs-CRP levels with PLC risk

Group	Incidence density/One hundred thousand	Cases/person-years	Crude models		Adjusted models
Group	Incidence density/One hundred thousand	Cases/person-years	HR (95%CI)	P-value	HR (95%CI)	P-value
MetS-CRP-	32.21	276/856820	Ref		Ref
MetS-CRP +	45.36	78/171939	1.39(1.08,1.79)	0.010	1.36(1.05,1.75)	0.019
MetS + CRP-	28.97	23/79392	0.90(0.59,1.38)	0.624	1.18(0.76,1.82)	0.390
MetS + CRP +	66.90	18/26905	2.08(1.29,3.35)	0.003	2.91(1.77,4.81)	< 0.001

Adjusted models were adjusted for age (10-year age classes), sex, family income, educational background, marital status, HBV infection, cirrhosis, fatty liver, BMI, TC, ALT, SUA, smoking status, drinking status, physical activity, sedentary lifestyle, tea consumption, salt intake, high-fat diet, family history of cancer

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