Fig. 4
From: Blockade of the amino acid transporter SLC6A14 suppresses tumor growth in colorectal Cancer
Knockdown or blockade of SLC6A14 suppresses cell proliferation and promotes apoptosis. A Cell cycle analysis G1/S transition of the HCT116 or Caco2 cells transfected with SLC6A14-siRNA or treated with α-MT by flow cytometry. B Quantification of cell cycle analysis. C The cell apoptosis of the HCT116 or Caco2 cells transfected with SLC6A14-siRNA or treated with α-MT cultured in FBS-free medium was stained with Annexin-V/PI and examined by flow cytometry. D The quantification of apoptotic cells identified as PI-negative and Annexin-V-positive staining. The data are expressed as the mean ± SD of three independent experiments. *P < 0.05