Fig. 8

(A) Gene set enrichment analysis (GSEA) of hub genes in the TCGA COAD-READ dataset. The association between expression of (B) SLC4A4, (C) MMP1, (D) MMP3, (E) GCG, (F) CXCL3, (G) CXCL1, (H) CLCA4, and (I) CLCA4 as mRNAs, besides (J) UCA1, (K) LINC00449, and (L) TPTEP1 as lncRNAs, and (M) has-miR-1301, (N) has-miR-132, (O) has-miR-339, and (P) has-miR-497 as miRNAs with OS of all patients in the TCGA COAD-READ dataset. Moreover, Kaplan-Meier analyses of DFS for LINC00974 with the (Q) optimal- and (R) median-cut-off values in patients with CRC have been shown. The yellow line indicates high expression groups and the blue line represents the low expression group