Fig. 2

Lyc inhibited HUVECs migration and tube formation in vitro. A Transwell assay was performed to measure cell migration in HUVECs treated with Lyc and/or sunitinib. The bar graphes represented 25 μm. The relative migration of cells was quantified. B Wound healing assay was used to detect migration distances of these cells treated with Lyc and/or sunitinib for different time. The bar graphes represented 25 μm. The quantification of relative wound area was performed. C Tube formation assay detected formed tubes of HUVECs treated with Lyc and/or sunitinib. Calculating branch points per field was used to quantify the ability of tube formation. The bar graphes represented 50 μm. Data represents mean ± SD, *p < 0.05, n = 3