Exosome-derived lnc-HOXB8-1:2 induces tumor-associated macrophage infiltration to promote neuroendocrine differentiated colorectal cancer progression by sponging hsa-miR-6825-5p

Table 1 Baseline data of neuroendocrine differentiated colorectal cancer patients

Factors	No. Patients				\({\chi }^{2}\)/\(U\)	\({\rm P}\)
Factors	Total	Percentage (%)	NED	Non-NED	\({\chi }^{2}\)/\(U\)	\({\rm P}\)
All patients	105	100.0	18	87
Gender					1.559^a	0.212
Male	62	59.0	13	49
Female	43	41.0	5	38
Age					724.5^b	0.498
≤ 50	24	22.9	3	21
> 50	81	77.1	15	66
Primary tumor site					0.303^a	0.582
Colon	58	55.2	11	47
Rectum	47	44.8	7	40
Tumor differentiation					736.5^b	0.593
High	18	17.1	3	15
Moderate	81	77.1	13	68
Low	6	5.7	2	4
TNM stage					724.5^b	0.603
I	13	12.4	3	10
II	34	32.4	4	30
III	42	40.0	7	35
IV	16	15.2	4	12
Lymphatic metastasis					0.043^a	0.836
Positive	56	53.3	10	46
Negative	49	46.7	8	41
Simultaneous distant metastasis					0.298^c	0.585
Yes	16	15.2	4	12
No	89	84.8	14	75

NED Neuroendocrine differentiation group, non-NED Non-neuroendocrine differentiation group
^a The chi-square test, \({\chi }^{2}\)
^b The Mann–Whitney U rank-sum test, \(U\)
^c The chi-square test with Yates’ correction, \({\chi }^{2}\)

ISSN: 1471-2407