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Fig. 5 | BMC Cancer

Fig. 5

From: High-throughput circular RNA sequencing reveals the profiles of circular RNA in non-cirrhotic hepatocellular carcinoma

Fig. 5

Biological functions of four most prominent dysregulated circRNAs were verified by in vitro experiments. A-D Knockdown effect of special siRNAs for these circRNAs was verified by qRT-PCR. E-H CCK-8 assay results showed that knockdown of these circRNAs significantly affects the proliferation of HCC cells. I Colony formation assay showed the influence of these circRNAs on the survival of HCC cells. J Wound healing assay was used to evaluate the biological function of these circRNAs in migration of HCC cells. **P < 0.01, ***P < 0.001. Similar results were obtained in 3 independent experiments

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