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Table 1 The characteristics of all patients with lung adenocarcinoma

From: Associations of IFT20 and GM130 protein expressions with clinicopathological features and survival of patients with lung adenocarcinoma

Variables

IFT20 protein expression

P value

GM130 protein expression

P value

Negative (n = 67)

Positive (n = 168)

Negative (n = 84)

Positive (n = 151)

Age (years, Mean ± SD)

57.25 ± 9.58

56.20 ± 9.86

0.458

57.36 ± 9.62

56.03 ± 9.86

0.318

Gender, (Male, n, %)

47(70.15)

90(53.57)

0.024

55(65.48)

82(54.30)

0.096

Smoking status (n, %)

  

0.009

  

0.177

 Current smoking

28(41.79)

44(26.19)

 

27(32.14)

45(29.80)

 

 Never smoking

28(41.79)

107(63.69)

 

43(51.19)

92(60.93)

 

 Former smoking

11(16.42)

17(10.12)

 

14(16.67)

14(9.27)

 

Smoking amount, pack-year

22.05 ± 25.24

13.30 ± 23.06

0.011

20.67 ± 27.98

13.09 ± 21.04

0.020

Differentiated types of tumors (n, %)

  

0.377

  

0.049

 Poorly

20(29.85)

51(30.36)

 

33(39.29)

38(25.17)

 

 Moderately

39(58.21)

85(50.60)

 

36(42.86)

88(58.28)

 

 Well

8(11.94)

32(19.05)

 

15(17.86)

25(16.56)

 

Ki67

  

0.441

  

0.222

 < 50%

56(83.58)

133(79.17)

 

64(76.19)

125(82.78)

 

 ≥50%

11(16.42)

35(20.83)

 

20(23.81)

26(17.22)

 

Tumor size (cm)

4.93 ± 2.56

4.43 ± 2.06

0.117

5.02 ± 2.67

4.32 ± 1.89

0.019

T stages (n, %)

  

0.012

  

0.206

 T1 ~ T2

36(53.73)

119(70.83)

 

51(60.71)

104(68.87)

 

 T3 ~ T4

31(46.27)

49(29.17)

 

33(39.29)

47(31.13)

 

N stages (n, %)

  

0.048

  

0.084

 N0 ~ N1

19(28.36)

71(42.26)

 

26(30.95)

64(42.38)

 

 N2 ~ N3

48(71.64)

97(57.74)

 

58(69.05)

87(57.62)

 

M stages (n, %)

  

0.193

  

0.785

 M0

50(74.63)

138(82.14)

 

68(80.95)

120(79.47)

 

 M1

17(25.37)

30(17.86)

 

16(19.05)

31(20.53)

 

TNM stages (n, %)

  

0.182

  

0.613

 I stage

9(13.43)

43(25.60)

 

15(17.86)

37(24.50)

 

 II stage

12(17.91)

25(14.88)

 

15(17.86)

22(14.57)

 

 III stage

29(43.28)

70(41.67)

 

38(45.24)

61(40.40)

 

 IV stage

17(25.37)

30(17.86)

 

16(19.05)

31(20.53)

 

Chemotherapy/radiotherapy (yes, n, %)

39(58.21)

110(65.48)

0.296

51(60.71)

98(64.90)

0.523

Lymphatic metastasis (yes, n, %)

48(71.64)

97(57.74)

0.048

58(69.05)

87(57.62)

0.084

Distant metastasis (yes, n, %)

17(25.37)

30(17.86)

0.193

16(19.05)

31(20.53)

0.785

Alive (yes, n, %)

14(20.90)

42(25.00)

0.505

15(17.86)

41(27.15)

0.109

Overall survival (years, Mean ± SD)

2.42 ± 1.64

3.00 ± 1.71

0.018

2.57 ± 1.73

2.99 ± 1.69

0.066