Fig. 6

Correlation analysis between MTOR expression and TIICs in CRC. A The scatterplots display the correlations between MTOR expression and infiltrating B cells, CD8⁺ T cells, CD4⁺ T cells, macrophages, neutrophils and dendritic cells in COAD and READ. B The boxplot shows the correlation between MTOR copy number variation and infiltrating B cells, CD8⁺ T cells, CD4⁺ T cells, macrophages, neutrophils and dendritic cells in COAD and READ. *p < 0.05, ***p < 0.001. C The stacked bar chart shows the different proportion of TIICs between high and low MTOR expression groups in CRC. D The box plot shows the different fraction of TIICs between high and low MTOR expression groups in CRC. ns, not significant, *p < 0.05, **p < 0.01, ***p < 0.001. E The box plot shows differences in immune checkpoint genes expression between high and low MTOR expression groups in CRC. *p < 0.05, **p < 0.01, ***p < 0.001. CRC, colorectal cancer; TIICs, tumor-infiltrating immune cells; COAD, Colon adenocarcinoma; READ, Rectum adenocarcinoma