Table 3 Dose calculation of trifluridine/tipiracil according to BSA
Dose (mg/m2) | BSA (m2) | Dose in mg (BID) | Tablets per Dose (BID) 15 mg/6.14 mg | Tablets per Dose (BID) 20 mg/8.19 mg | Total daily dose (mg) |
|---|---|---|---|---|---|
35 | < 1.07 | 35 | 1 | 1 | 70 |
1.07–1.22 | 40 | 0 | 2 | 80 | |
1.23–1.37 | 45 | 3 | 0 | 90 | |
1.38–1.52 | 50 | 2 | 1 | 100 | |
1.53–1.68 | 55 | 1 | 2 | 110 | |
1.69–1.83 | 60 | 0 | 3 | 120 | |
1.84–1.98 | 65 | 3 | 1 | 130 | |
1.99–2.14 | 70 | 2 | 2 | 140 | |
2.15–2.29 | 75 | 1 | 3 | 150 | |
≥ 2.30 | 80 | 0 | 4 | 160 |