Table 5 Criteria for S-1 skipping and reduction of docetaxel and S-1 from the next course in the postoperative DS chemotherapy
S-1 skipping | Docetaxel and S-1 reduction from the next course | |
|---|---|---|
Neutrophil count decreased | Grade 3 | Grade 4 |
Platelet count decreased | Grade 3 | Grade 3 |
Creatinine increased | >1.5 mg/dL | >1.5 mg/dL |
Febrile neutropenia | – | Grade 3 |
Infection | – | Grade 3 |
Diarrhea, Oral mucositis, Rash | Grade 2 | Grade 3 |
Nausea, Fatigue | Grade 2 | Grade 3 |
Vomiting, Anorexia | Grade 2 | Grade 3 |
Infusion reaction | Grade 2 | – |
Hypernatremia, Hyponatremia, Hyperkalemia, Hypokalemia | Grade 2 | Grade 3 |