Skip to main content

Table 3 Treatment exposure

From: Safety and efficacy of irinotecan, oxaliplatin, and capecitabine (XELOXIRI) regimen with or without targeted drugs in patients with metastatic colorectal cancer: a retrospective cohort study

Reasons for discontinuing XELOXIRI

n = 61 (%)

Surgery

26 (42.62%)

Maintenance treatment

9 (14.75%)

AEs

4 (6.56%)

Disease progression

12 (19.67%)

Loss to follow-up

5 (8.20%)

Radiotherapy

3 (4.92%)

Ablation

1 (1.64%)

Drug discontinuation

n (%)

Any drug discontinuation

19 (31.15%)

Oxaliplatin

5 (8.20%)

Irinotecan

10 (16.39%)

Capecitabin

1 (1.64%)

Oxaliplatin and irinotecan

2 (3.28%)

Irinotecan and capecitabin

1 (1.64%)

Dose intensity

mg/m2/week

Oxaliplatin

 mean dose intensity

36.95

 median dose intensity

37.31

Irinotecan

 mean dose intensity

71.41

 median dose intensity

71.41

Capecitabin

 mean dose intensity

5599.75

 median dose intensity

5599.75

  1. AE Adverse event, XELOXIRI Capecitabine, oxaliplatin and irinotecan