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Table 3 Incidence trends and five-year age-standardized incidence rates (ASR) per 100,000 person-years with 95% confidence intervals (CIs) of pediatric CNS tumors in Finland

From: Incidence trends of childhood central nervous system tumors in Finland 1990–2017

 

1990–2017

1990–1994

2001–2005

2013–2017

 

APC (95% CI)

N

ASR (95%)

N

ASR (95%)

N

ASR (95%)

Total

0.8 (0.2, 1.4)

201

4.12 (4.03, 4.21)

195

4.25 (4.15, 4.34)

216

4.81 (4.71, 4.91)

Sex

 Boys

0.9 (0.1, 1.8)

105

4.20 (4.07, 4.32)

117

4.99 (4.85, 5.14)

117

5.09 (4.94, 5.24)

 Girls

0.7 (−0.3, 1.7)

96

4.04 (3.91, 4.17)

78

3.47 (3.35, 3.60)

99

4.52 (4.37, 4.66)

Age group

 0–4 years

0.4 (−0.8, 1.5)

85

5.28 (4.16, 6.41)

68

4.78 (3.65, 5.92)

82

5.60 (4.39, 6.82)

 5–9 years

1.0 (−0.4, 2.3)

61

3.81 (2.86, 4.77)

66

4.30 (3.26, 5.33)

70

4.57 (3.50, 5.64)

 10–14 years

1.1 (−0.3, 2.4)

55

3.37 (2.48, 4.26)

61

3.71 (2.78, 4.65)

64

4.33 (3.27, 5.39)

Tumor grade

 Grade I

1.0 (0.1, 2.0)

80

1.64 (1.59, 1.70)

96

2.09 (2.02, 2.15)

98

2.20 (2.13, 2.27)

 Grade II

−0.5 (−2.5, 1.5)

41

0.85 (0.81, 0.89)

27

0.59 (0.56, 0.63)

26

0.57 (0.54, 0.61)

 Grade III

2.6 (0.0, 5.3)

13

0.27 (0.24, 0.29)

20

0.44 (0.40, 0.47)

25

0.55 (0.51, 0.58)

 Grade IV

0.7 (−0.4, 1.8)

48

0.97 (0.93, 1.02)

42

0.91 (0.87, 0.96)

45

1.00 (0.95, 1.04)

Tumor location

 Supratentorial

−0.9 (−2.1, 0.4)

65

1.33 (1.28, 1.38)

74

1.61 (1.55, 1.67)

50

1.11 (1.06, 1.16)

 Infratentorial

0.4 (−0.8, 1.6)

86

1.76 (1.70, 1.82)

86

1.87 (1.81, 1.93)

88

1.95 (1.89, 2.02)

 Cerebellum

0.1 (−1.2, 1.4)

59

1.20 (1.15, 1.25)

59

1.28 (1.23, 1.33)

55

1.22 (1.17, 1.27)

 Brain stem

1.6 (−0.4, 3.7)

26

0.54 (0.51, 0.57)

26

0.57 (0.54, 0.61)

32

0.71 (0.67, 0.75)

 Spinal cord

1.0 (−1.3, 3.4)

15

0.31 (0.29, 0.34)

11

0.24 (0.22, 0.26)

14

0.32 (0.29, 0.34)

 Unspecified

2.5 (−2.5, 7.8)

30

0.61 (0.58, 0.65)

20

0.44 (0.41, 0.47)

58

1.29 (1.24, 1.35)

Histology

 Diffuse astrocytic tumors

−1.7 (−3.5, 0.1)

44

0.91 (0.87, 0.95)

33

0.72 (0.68, 0.76)

23

0.52 (0.48, 0.55)

 Other astrocytic tumors

0.6 (−0.6, 1.8)

63

1.30 (1.25, 1.35)

67

1.45 (1.40, 1.51)

66

1.48 (1.42, 1.54)

 Pilocytic astrocytoma

0.4 (−0.9, 1.7)

56

1.15 (1.10, 1.20)

63

1.37 (1.31, 1.42)

58

1.30 (1.24, 1.35)

 Ependymal tumors

1.9 (−0.5, 4.4)

13

0.27 (0.25, 0.29)

20

0.44 (0.41, 0.47)

23

0.50 (0.47, 0.54)

 Neuronal/glial tumors

1.4 (−1.3, 4.2)

13

0.27 (0.24, 0.29)

23

0.50 (0.47, 0.53)

23

0.52 (0.48, 0.55)

 Embryonal tumors

1.2 (−0.1, 2.6)

34

0.68 (0.65, 0.72)

27

0.59 (0.55, 0.62)

39

0.86 (0.82, 0.90)

 Medulloblastoma

1.6 (−0.4, 3.6)

22

0.45 (0.42, 0.48)

14

0.31 (0.28, 0.33)

30

0.66 (0.62, 0.70)

 Other tumors

1.5 (−0.0, 3.1)

34

0.69 (0.65, 0.73)

25

0.55 (0.51, 0.58)

42

0.93 (0.89, 0.98)