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Fig. 5 | BMC Cancer

Fig. 5

From: Metformin attenuates the production and proliferative effects of prolactin induced by medroxyprogesterone acetate during fertility-sparing treatment for endometrial cancer

Fig. 5

PRL induced the activation of ERK1/2 and rpS6 and metformin attenuated this effect. We preliminary observed that phospho-ERK1/2 levels were the most elevated at 6 h after the addition of PRL, and this increase was time-dependent (data not shown).Total protein extracted from HEC1B cells a and HEC265 cells b exposed to 500 ng/mL of PRL with or without 1 mM metformin for 6 h was subjected to western blotting. Met indicates metformin

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BMC Cancer

ISSN: 1471-2407

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