Table 2 Screening of probable marker genes highly correlated with cellular sensitivity to key therapeutic drugs

TXT

AGR2

anterior gradient 2 homolog

0.7009

0.7009

0.4913

0.0036

0.6974

0.6974

0.4864

0.0039

SYNGR1

synaptogyrin 1

0.6262

0.6262

0.3921

0.0125

0.4533

0.4533

0.2055

0.0897

PDE4D

phosphodiesterase 4D, cAMP-specific

0.5885

0.5885

0.3463

0.0210

0.7462

0.7462

0.5568

0.0014

RAB15

RAB15, member RAS oncogene family

0.5298

0.5298

0.2807

0.0422

0.6366

0.6366

0.4053

0.0107

CDDP

NOTCH2NL

notch 2 N-terminal like

0.7575

0.7575

0.5738

0.0011

0.0361

0.0361

0.0013

0.8984

KLK11

kallikrein-related peptidase 11

−0.7526

0.7526

0.5664

0.0012

−0.6700

0.6700

0.4489

0.0063

NINJ2

ninjurin 2

−0.8180

0.8180

0.6691

0.0002

−0.8532

0.8532

0.7280

0.0001

PTGS1

prostaglandin-endoperoxide synthase 1

−0.8309

0.8309

0.6904

0.0001

−0.7722

0.7722

0.5963

0.0007

5-FU

GOLGA8A

golgin A8 family, member A

0.7857

0.7857

0.6173

0.0005

−0.1010

0.1010

0.0102

0.7202

JDP2

Jun dimerization protein 2

0.7665

0.7665

0.5875

0.0009

0.4067

0.4067

0.1654

0.1325

STXBP1

syntaxin binding protein 1

−0.7504

0.7504

0.5631

0.0013

−0.3824

0.3824

0.1462

0.1595

CDC25B

cell division cycle 25 homolog B

−0.7528

0.7528

0.5667

0.0012

−0.6434

0.6434

0.4140

0.0097

PBX3

pre-B-cell leukemia homeobox 3

−0.7599

0.7599

0.5774

0.0010

−0.5457

0.5457

0.2978

0.0354

SEPW1

selenoprotein W, 1

−0.7648

0.7648

0.5849

0.0009

−0.7058

0.7058

0.4982

0.0033

RCAN3

RCAN family member 3

−0.8006

0.8006

0.6410

0.0003

−0.6375

0.6375

0.4064

0.0106

ZNF584

zinc finger protein 584

−0.8344

0.8344

0.6962

0.0001

0.0574

0.0574

0.0033

0.8390

(AGR2)

0.5883

0.5883

0.3461

0.0211