Table 3 Total avoidable expenditure (R$) and additional quantities that could have been purchased at the lowest weighted average pricea by medicine (units) and purchaser category. Brazil, 2013–2019
MINISTRY OF EDUCATION | ||||||||||||||||
Medicine& | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | Total | ||||||||
AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | |
Anastrozole 1 mg1 | 310,500s | 235,227 | 350,880s | 265,818 | 58,597s | 48,030 | 268,443s | 221,854 | 83,946s | 68,249 | NA | NA | 387,309o | 1,046,781 | 1,459,675 | 1,885,959 |
Docetaxel 40 mg2 | 390,477o | 4067 | NA | NA | 768,635o | 12,397 | NA | NA | 552,559s | 7467 | 391,184s | 5927 | 10,923d | 155 | 2,113,778 | 30,014 |
Exemestane 25 mg3 | 260,230s | 15,536 | NA | NA | 241,621s | 13,240 | 117,260o | 6013 | 27,111o | 1276 | 101,956s | 5826 | 126,217s | 28,048 | 874,396 | 69,939 |
Letrozole 2.5 mg1 | NA | NA | NA | NA | 80,412s | 12,092 | 539,006o | 56,001 | NA | NA | 340,783s | 54,525 | NA | NA | 960,201 | 122,618 |
Paclitaxel 6 mg2 | 301,885s | 173,497 | NA | NA | 1,672,640s | 1,161,556 | 712,742d | 329,973 | NA | NA | NA | NA | 1,212,257s | 396,162 | 3,899,524 | 2,061,188 |
Tamoxifen 20 mg1 | 271,405s | 678,513 | NA | NA | 2,451,137s | 4,085,228 | NA | NA | 1,158,080s | 1,447,600 | NA | NA | NA | NA | 3,880,623 | 6,211,342 |
Trastuzumab 440 mg2 | 3,131,527o | 295 | 920,266o | 90 | 1,304,827o | 131 | 328,739o | 32 | 1,506,941o | 144 | 3,185,909s | 315 | 843,025d | 100 | 11,221,235 | 1107 |
Vinorelbine 10 mg4 | 97,010s | 3789 | 188,306s | 8559 | 153,513s | 6823 | 48,856s | 1816 | 230,746s | 8125 | 506,126s | 20,574 | 49,657s | 2104 | 1,274,214 | 51,791 |
Vinorelbine 20 mg4 | 41,334d | 304 | 14,394d | 114 | 27,455s | 242 | 20,011d | 170 | 61,538d | 531 | 21,901s | 185 | 51,889d | 504 | 238,522 | 2050 |
Vinorelbine 30 mg4 | 107,430d | 567 | 41,584d | 219 | 63,109s | 370 | 92,181s | 539 | 148,594d | 869 | 48,123d | 271 | 273,096o | 1908 | 774,117 | 4744 |
MINISTRY OF HEALTH | ||||||||||||||||
Medicine& | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | Total | ||||||||
AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | |
Anastrozole 1 mg1 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 82,660e | 99,591 | 99,310o | 268,405 | 181,970 | 367,995 |
Docetaxel 40 mg2 | 3,247,794o | 33,831 | 147,224e | 2217 | 206,006o | 3323 | 64,661e | 913 | NA | NA | NA | NA | NA | NA | 3,665,685 | 40,284 |
Exemestane 25 mg3 | NA | NA | NA | NA | NA | NA | 96,606o | 4954 | 96,196o | 4527 | NA | NA | NA | NA | 192,801 | 9481 |
Letrozole 2.5 mg1 | 1362e | 164 | NA | NA | NA | NA | NA | NA | 230e | 25 | NA | NA | 16,162e | 5213 | 17,753 | 5402 |
Paclitaxel 6 mg2 | NA | NA | 5711e | 2884 | NA | NA | 61,613d | 28,525 | 171,549e | 58,350 | 1,068,095e | 468,463 | NA | NA | 1,306,968 | 558,222 |
Tamoxifen 20 mg1 | NA | NA | NA | NA | NA | NA | 1,285,271e | 918,051 | NA | NA | NA | NA | NA | NA | 1,285,271 | 918,051 |
Trastuzumab 440 mg2 | 8,496,516o | 801 | 4,553,299o | 447 | 2,594,719o | 260 | NA | NA | 3,746,929o | 358 | NA | NA | 570,309d | 67 | 19,961,772 | 1934 |
Vinorelbine 10 mg4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Vinorelbine 20 mg4 | 31,586d | 232 | NA | NA | NA | NA | 10,337d | 88 | 36,843d | 318 | NA | NA | 48,881d | 475 | 127,648 | 1113 |
Vinorelbine 30 mg4 | 240,228d | 1267 | NA | NA | NA | NA | NA | NA | 62,664d | 366 | 1021d | 6 | 112,578o | 787 | 416,490 | 2426 |
MINISTRY OF DEFENSE | ||||||||||||||||
Medicine& | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | Total | ||||||||
AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | |
Anastrozole 1 mg1 | 175,371s | 132,857 | 301,078s | 228,090 | 364,487s | 298,759 | 71,568s | 59,147 | 1,160,270s | 943,309 | 229,449e | 276,445 | 185,286o | 500,773 | 2,487,509 | 2,439,380 |
Docetaxel 40 mg2 | 28,038o | 292 | 159,722e | 2405 | 945,109o | 15,244 | 81,561e | 1152 | 592,045s | 8001 | 1,118,551s | 16,948 | NA | NA | 2,925,026 | 44,042 |
Exemestane 25 mg3 | 219,671s | 13,115 | 13,113e | 656 | 96,936s | 5312 | 65,326o | 3350 | 156,005o | 7341 | 121,042s | 6917 | 572,184s | 127,152 | 1,244,278 | 163,842 |
Letrozole 2.5 mg1 | 4687e | 563 | 40,085e | 5257 | 82,559s | 12,415 | 26,446o | 2748 | 83,644e | 8946 | 244,233s | 39,077 | 318,416e | 102,715 | 800,071 | 171,721 |
Paclitaxel 6 mg2 | 193,477s | 111,194 | 1,335,805e | 674,649 | 249,584s | 173,322 | NA | NA | 79,445e | 27,022 | 325,684e | 142,844 | 337,189s | 110,193 | 2,521,184 | 1,239,223 |
Tamoxifen 20 mg1 | 72,358s | 180,896 | 31,192s | 51,986 | 295,977s | 493,295 | 22,452e | 16,037 | 97,743s | 122,179 | 76,082s | 95,103 | NA | NA | 595,805 | 959,496 |
Trastuzumab 440 mg2 | 3,269,234o | 308 | 4,268,039o | 419 | 4,736,421o | 475 | 639,984o | 62 | 6,876,263o | 657 | 1,407,957s | 139 | NA | NA | 21,197,898 | 2060 |
Vinorelbine 10 mg4 | 9412s | 368 | 65,409s | 2973 | 36,320s | 1614 | 8213s | 305 | 30,110s | 1060 | 33,388s | 1357 | 57,289s | 2427 | 240,141 | 10,105 |
Vinorelbine 20 mg4 | NA | NA | NA | NA | 33,911s | 299 | NA | NA | NA | NA | 323s | 3 | NA | NA | 34,234 | 301 |
Vinorelbine 30 mg4 | NA | NA | NA | NA | 19,258s | 113 | 2632s | 15 | NA | NA | NA | NA | 41,251o | 288 | 63,141 | 417 |
OTHER INSTITUTIONS | ||||||||||||||||
Medicine& | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | Total | ||||||||
AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | AE (R$) | Units | |
Anastrozole 1 mg1 | 273,649s | 207,310 | 148,643s | 112,608 | 215,818s | 176,900 | 456,011s | 376,868 | 76,409s | 62,121 | 218,657e | 263,442 | NA | NA | 1,389,186 | 1,199,249 |
Docetaxel 40 mg2 | NA | NA | 213,948e | 3222 | NA | NA | 2,007,159e | 28,350 | 322,482s | 4358 | 491,028s | 7440 | NA | NA | 3,034,617 | 43,369 |
Exemestane 25 mg3 | 15,042s | 898 | 28,088e | 1404 | 36,445s | 1997 | NA | NA | NA | NA | 280,207s | 16,012 | 610,704s | 135,712 | 970,486 | 156,023 |
Letrozole 2.5 mg1 | 49,663e | 5966 | 1082e | 142 | 3500s | 526 | NA | NA | 108,797e | 11,636 | 4065s | 650 | 5913e | 1907 | 173,020 | 20,827 |
Paclitaxel 6 mg2 | 411,748s | 236,637 | 245,363e | 123,921 | 362,000s | 251,389 | 39,448d | 18,263 | 263,379e | 89,585 | 404,387e | 177,363 | 104,450s | 34,134 | 1,830,775 | 931,291 |
Tamoxifen 20 mg1 | 568,902s | 1,422,254 | 918,086s | 1,530,144 | 213,870s | 356,450 | 168,534e | 120,382 | NA | NA | 140,916s | 176,146 | NA | NA | 2,010,309 | 3,605,375 |
Trastuzumab 440 mg2 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1,050,590s | 104 | 1,996,514d | 236 | 3,047,104 | 340 |
Vinorelbine 10 mg4 | 3422s | 134 | 34,022s | 1546 | 7198s | 320 | 28,195s | 1048 | 428,934s | 15,103 | 114,889s | 4670 | 73,749s | 3125 | 690,408 | 25,947 |
Vinorelbine 20 mg4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 22,812d | 221 | 22,812 | 221 |
Vinorelbine 30 mg4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |