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Fig. 2 | BMC Cancer

Fig. 2

From: Anesthetic propofol enhances cisplatin-sensitivity of non-small cell lung cancer cells through N6-methyladenosine-dependently regulating the miR-486-5p/RAP1-NF-κB axis

Fig. 2

Propofol inhibited cell proliferation and promoted cell apoptosis in DDP-resistant NSCLC cells treated with DDP. A549/DDP and SKMES/DDP cells were pretreated by low concentration of propofol (5 μg/mL) or high concentration of propofol (10 μg/mL), and then treated with DDP (40 μM). a The cell viability at different time (0, 24, 48, 72, 96 h) was evaluated through CCK8 assay. b The colony formation ability was measured by Giemsa staining. c The apoptosis was detected by flow cytometry. *P < 0.05. N, without propofol. L, low concentration of propofol. H, high concentration of propofol

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