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Table 2 Univariate and multivariate analyses of recurrence-free survival

From: C-reactive protein/albumin ratio and Glasgow prognostic score are associated with prognosis and infiltration of Foxp3+ or CD3+ lymphocytes in colorectal liver metastasis

 

N

Event

Univariate

Multivariate

95% CI

HR

p-value

95% CI

HR

p-value

Sex

        

 Female

42

26

1

   

 Male

75

52

0.74-1.90

1.12

0.473

   

Age

        

 ≥70

40

26

1

   

 <70

77

52

0.81-2.07

1.29

0.288

   

Primary tumor location

        

 Left

85

55

1

   

 Right

32

23

0.71-1.89

1.16

0.558

   

NAC

        

 Yes

47

37

1

1

 No

70

41

0.27-0.66

0.42

0.0002*

0.37-1.05

0.62

0.075

Preoperative CEA

        

 ≥5

83

57

1

   

 <5

34

21

0.52-1.42

0.86

0.546

   

Onset

        

 Synchronous

61

48

1

1

 Metachronous

56

30

0.23-0.59

0.37

<.0001*

0.28-0.78

0.47

0.0038*

Tumor location

        

 Hemilobar

72

43

1

1

 Bilobar

45

35

1.05-2.59

1.65

0.0292*

0.67-2.16

1.21

0.531

Tumor diameter

        

 ≥50

23

17

1

   

 <50

94

61

0.42-1.23

0.72

0.223

   

Tumor number

        

 Multiple

63

46

1

1

 Solitary

54

32

0.38-0.94

0.60

0.026*

0.53-1.80

0.98

0.952

NLR

        

 ≥2.03

59

38

1

   

 <2.03

58

40

0.58-1.41

0.91

0.665

   

PLR

        

 ≥134

59

38

1

   

 <134

58

40

0.60-1.47

0.94

0.784

   

CAR

        

 ≥0.030

59

39

1

   

 <0.030

58

39

0.50-1.21

0.78

0.271

   

GPS

        

 1/2

13

9

1

   

 0

104

69

0.43-1.75

0.87

0.696

   
  1. CAR C-reactive protein/albumin ratio, CEA carcinoembryonic antigen, CI confidence interval, HR hazard ratio, GPS Glasgow prognostic score, NAC neoadjuvant chemotherapy, NLR neutrophil/lymphocyte ratio, PLR platelet/lymphocyte ratio
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BMC Cancer

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