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Fig. 4 | BMC Cancer

Fig. 4

From: Targeting the transcriptional activity of STAT3 by a novel fusion protein

Fig. 4

KRAB-STAT3 inhibits cell migration and invasion. A, Transwell assay of control and KRAB-STAT3-expressing HeLa and A375 cells. K-S: KRAB-STAT3. Bars = 50 μm. B, Migrated cells per view of control and HeLa cells. C, Migrated cells per view of control and A375 cells represented as mean ± SD; n = 3; Student’s t-test. D, E, Lysosome pH analysis of HeLa and A375 cells. F-G, Mitochondria ROS production detection using mitoSOX, A.U., Any unit. H-I, Mitochondrial membrane potential detection using TFRM. J-K, ATP content in HeLa and A375 cells represented as mean ± SD; n = 3; Student’s t-test

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