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Table 3 Baseline characteristics of colorectal cancer patients according to c-type lectin-like receptor 2 levels

From: Association between c-type lectin-like receptor 2 and microsatellite instability in colorectal cancer: a cross-sectional study

Variables

Total

CLEC-2 ≤ 166.3

CLEC-2 > 166.3

p value

Age (years)

   

0.298

  ≤ 65

309 (71.9)

247 (70.8)

62 (76.5)

 

  > 65

121 (28.1)

102 (29.2)

19 (23.5)

 

Gender

   

0.432

 Male

245 (57.0)

202 (57.9)

43 (53.1)

 

 Female

185 (43.0)

147 (42.1)

38 (46.9)

 

BMI (kg/m2)

23.4 ± 3.2

23.9 ± 3.2

23.3 ± 3.2

0.166

Current smoker

   

0.906

 Yes

183 (42.6)

149 (42.0)

34 (42.0)

 

 No

247 (57.4)

200 (58.0)

47 (58.0)

 

Drinker

   

0.401

 Yes

139 (32.3)

116 (33.2)

23 (28.4)

 

 No

291 (67.7)

233 (66.8)

58 (71.6)

 

WBC (×109/L)

7.09 ± 2.44

7.35 ± 3.16

7.03 ± 2.25

0.393

Hemoglobin (g/L)

132.9 ± 23.4

129.4 ± 25.2

133.7 ± 23.0

0.141

Platelet count (×109/L)

270.0 ± 87.8

265.6 ± 82.8

286.9 ± 105.7

0.093

Creatinine (umol/L)

81.1 ± 18.6

83.0 ± 28.4

80.6 ± 15.4

0.467

CEA (ng/ml)

4.37 (2.03–11.31)

3.82 (1.94–13.70)

4.67 (2.12–10.67)

0.768

Tumor size (cm)

   

0.260

  < 5.0

278 (64.7)

230 (65.9)

48 (59.3)

 

  ≥ 5.0

152 (35.3)

119 (34.1)

33 (40.7)

 

Tumor location

   

0.687

 Proximal

157 (36.5)

129 (37.0)

28 (34.6)

 

 Distal

273 (63.5)

220 (63.0)

53 (65.4)

 

Histological type

   

0.383

 Non-mucinous

359 (83.5)

294 (84.2)

65 (80.2)

 

 Mucinous

71 (28.6)

55 (15.8)

16 (19.8)

 

Histological grade

   

0.835

 Well/Moderately differentiated

359 (83.5)

292 (83.7)

67 (82.7)

 

 Poorly differentiated

71 (28.6)

57 (16.3)

14 (17.3)

 

Lymphatic invasion

   

0.285

 Absent

331 (77.0)

265 (75.9)

66 (81.5)

 

 Present

99 (23.0)

84 (24.1)

15 (18.5)

 

Perineural invasion

   

0.545

 Absent

365 (84.9)

298 (85.4)

67 (82.7)

 

 Present

65 (15.1)

51 (14.6)

14 (17.3)

 

T classification

   

0.693

 T1 + T2

63 (14.7)

50 (14.3)

13 (16.0)

 

 T3 + T4

367 (85.3)

299 (85.7)

68 (84.0)

 

Lymph node metastasis

   

0.665

 Absence

267 (62.1)

215 (61.6)

52 (64.2)

 

 Presence

163 (37.9)

134 (38.4)

29 (35.8)

 

Distant metastasis

   

0.707

 Absence

382 (88.8)

311 (89.1)

71 (87.7)

 

 Presence

48 (11.2)

38 (10.9)

10 (12.3)

 

Stage

   

0.392

 I-II

258 (60.0)

206 (59.0)

52 (64.2)

 

 III-I

172 (40.0)

143 (41.0)

29 (35.8)

 

MSI status

   

< 0.001***

 MSS

366 (85.1)

318 (91.1)

48 (59.3)

 

 MSI-H

64 (14.9)

31 (8.9)

33 (40.7)

 
  1. Values are means ± SD, median with interquartile range, or number with percentage. MSI, microsatellite instability; Other abbreviation as in Table 1. ***p < 0.001 vs. the values of CLEC-2 > 166.3 group