Fig. 7

LncRNA NDRG1/miR-96-5p axis regulates the PI3K/AKT pathway in OS cell lines. A. KEGG pathway analysis of the target genes of miR-96-5p predicted by Targetscan. B, C. The relative expression of p-PI3K/PI3K and p-AKT/AKT in MG63/143B cells transfected with si-Lnc-NDRG1 or si-NC. D, E. The relative protein expression of p-PI3K/PI3K and p-AKT/AKT in MG63/143B cells transfected with miR-96-5p mimics or inhibitor. F, G. The relative protein expression of p-PI3K/PI3K and p-AKT/AKT in MG63/143B cells transfected with si-NC + inhibitor NC; si-Lnc-NDRG1 + inhibitor NC; si-NC+ inhibitor or si-Lnc-NDRG1 + inhibitor respectively. All data are presented as the means ± SD of three independent experiments. ns. no significance, *P < 0.05, **P < 0.01, ***P < 0.001. (student’s t test)