Table 3 Characteristics of the tumours
Total | Non-Squamous | Squamous | p-value | |
|---|---|---|---|---|
Metastasis upon diagnosis | 0,333 | |||
No | 111 (1,3%) | 86 (1,2%) | 25 (1,5%) | |
Yes | 8604 (98,7%) | 6968 (98,8%) | 1636 (98,5%) | |
Number of metastatic sites | ||||
Mean (DT) | 2,21 (1,31) | 2,26 (1,34) | 2,00 (1,20) | < 0,001 |
1 | 3.189 (37,1%) | 2.490 (35,7%) | 699 (42,7%) | |
2 | 2.547 (29,6%) | 2.020 (29,0%) | 527 (32,2%) | |
3 | 1.551 (18,0%) | 1.311 (18,8%) | 240 (14,7%) | |
4 | 796 (9,3%) | 696 (10,0%) | 100 (6,1%) | |
> =5 | 521 (6,1%) | 451 (6,5%) | 70 (4,3%) | |
Liver | 1.385 (16,1%) | 1.120 (16,1%) | 265 (16,2%) | > 0,9 |
Bone | 3.224 (37,5%) | 2.704 (38,8%) | 520 (31,8%) | < 0,001 |
Thoracic lymphadenopathy | 2.063 (24,0%) | 1.686 (24,2%) | 377 (23,0%) | 0,335 |
Lung | 3.487 (40,5%) | 2.774 (39,8%) | 713 (43,6%) | 0,006 |
Non thoracic lymphadenopathy | 1.203 (14,0%) | 999 (14,3%) | 204 (12,5%) | 0,052 |
Adrenal | 1.600 (18,6%) | 1.336 (19,2%) | 264 (16,1%) | 0,004 |
Central Nervous System | 1.707 (19,8%) | 1.542 (22,1%) | 165 (10,1%) | < 0,001 |
Pleural Effusion | 1.628 (18,9%) | 1.381 (19,8%) | 247 (15,1%) | < 0,001 |
Pleural nodules | 802 (9,3%) | 657 (9,4%) | 145 (8,9%) | 0,508 |
Peritoneal cavity | 233 (2,7%) | 189 (2,7%) | 44 (2,7%) | > 0,9 |
Pericardial effusion | 294 (3,4%) | 253 (3,6%) | 41 (2,5%) | 0,023 |
Pancreas | 98 (1,1%) | 80 (1,1%) | 18 (1,1%) | > 0,9 |
Bilateral Lymphangitis | 198 (2,3%) | 170 (2,4%) | 28 (1,7%) | 0,082 |
Soft tissues | 347 (4,0%) | 277 (4,0%) | 70 (4,3%) | 0,576 |
Subcutaneous | 130 (1,5%) | 103 (1,5%) | 27 (1,7%) | 0,575 |
Meningeal carcinomatosis | 26 (0,3%) | 24 (0,3%) | 2 (0,1%) | 0,208 |
Stage T | 0,056 | |||
T1 | 797 (8,6%) | 712 (9,5%) | 85 (4,8%) | < 0,001 |
T1a | 201 (2,2%) | 179 (2,4%) | 22 (1,2%) | |
T1b | 385 (4,2%) | 343 (4,6%) | 42 (2,4%) | |
T1c | 211 (2,3%) | 190 (2,5%) | 21 (1,2%) | |
T2 | 1666 (18,0%) | 1.388 (18,6%) | 278 (15,7%) | |
T2a | 1105 (12,0%) | 922 (12,3%) | 183 (10,3%) | |
T2b | 561 (6,1%) | 466 (6,2%) | 95 (5,4%) | |
T3 | 1.458 (15,8%) | 1.162 (15,6%) | 296 (16,7%) | |
T4 | 3.056 (33,1%) | 2.294 (30,7%) | 762 (43%) | |
Stage N | ||||
NX | 2.369 (25,6%) | 1.968 (26,4%) | 401 (22,6%) | |
N0 | 1.011 (10,9%) | 820 (11%) | 191 (10,8%) | |
N1 | 660 (7,1%) | 530 (7,1%) | 130 (7,3%) | < 0,001 |
N2 | 2.556 (27,7%) | 1.992 (26,7%) | 564 (31,8%) | |
N3 | 2.643 (28,6%) | 2.157 (28,9%) | 486 (27,4%) | |
Stage M | ||||
M1a | 2.568 (27,8%) | 1.978 (26,5%) | 590 (33,3%) | |
M1b | 3.626 (39,2%) | 2.940 (39,4%) | 686 (38,7%) | |
M1c | 2.270 (24,6%) | 1.925 (25,8%) | 345 (19,5%) | < 0,001 |