Fig. 4
Tumor growth in xenograft model. A Representative bioluminescent images showing the tumor growth in xenograft NOD.CB17 mice injected with the Sk-Mel-28) and CTC- -AT up to 28 days after the inoculum. The color scale ranged from blue (just above the background noise; set to 1 × 107 photons / s / cm2 / sr) to red (at least 2.5 × 108 photons / s / cm2 / sr). B Dotted line represents the exponential model fit to the tumor size data points from mice. Tumor growth based on relative increase of median photon flux (photon/s) per second within ROI areas is significantly higher in mice inoculated with Sk-Mel-28 respect to CTC-AT line (p < 0.05)