Fig. 3
From: Non-invasive diagnosis strategy of hepatocellular carcinoma in low-risk population
The diagnostic flow of primary liver nodules in low-risk population. Each scenario to diagnose HCC depends on the number of major features of HCC. The major features are hyperenhancement (APHE), wash-out (WO) and enchancing capsule. I). If a liver nodule is with only one of the HCC major features, then all three ancillary features are needed to diagnose HCC. II). If a liver nodule meets two of the major features, HCC could be diagnosed by either a male patient with TNSI in nodule or a patient with AFP > 20 ng/ml. III). If a liver nodule meets all of the major features, HCC could be diagnosed under the circumstance where one of ancillary features is satisfied